Two cases of penicillium marneffei infection after kidney transplantation
10.3760/cma.j.cn421203-20250410-00070
- VernacularTitle:肾移植术后马尔尼菲篮状菌感染2例
- Author:
Shanda LI
1
;
Yuxiang CHEN
;
Zhuocheng LI
;
Yu ZHANG
;
Xuyuan ZHU
;
Liang GAO
;
Xiaojie MA
;
Tao LI
;
Hongtao JIANG
Author Information
1. 海南医科大学第二附属医院肾移植科，海口 570100
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Penicillium marneffei;
Metagenomic next-generation sequencing;
Immunosuppression;
Fungal infection;
Invasive;
Amphotericin B
- From:
Chinese Journal of Organ Transplantation
2025;46(11):793-796
- CountryChina
- Language:Chinese
-
Abstract:
This report presents two cases of penicillium marneffei infection occurring after kidney transplantation. Both recipients presented initially with gastrointestinal symptoms and were diagnosed early by metagenomic next generation sequencing (mNGS). Treatment included amphotericin B combined with voriconazole, adjustment of immunosuppressive therapy, and nutritional support, resulting in favorable outcomes. This study aims to characterize the clinical presentation, diagnostic challenges, and individualized treatment strategies for penicillium marneffei infection in kidney transplant recipients, providing valuable insights for clinical management.
