Research progress on the fibrinogen-like protein 1 in the pathogenesis of chronic metabolic diseases
10.3969/j.issn.1006-6187.2025.03.015
- VernacularTitle:纤维蛋白原样蛋白1在代谢性疾病发病中作用的研究进展
- Author:
Xiangjie WU
1
;
Xia DENG
1
;
Haoxiang LI
1
;
Ling YANG
1
Author Information
1. 212001 镇江,江苏大学附属医院内分泌代谢科
- Publication Type:Journal Article
- Keywords:
Fibrinogen-like protein 1;
Diabetes mellitus;
Metabolic diseases;
Metabolically associated fatty liver disease
- From:
Chinese Journal of Diabetes
2025;33(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Fibrinogen-like protein 1(FGL1)is a novel hepatic factor and a member of the fibrinogen family.FGL1 has diverse and complex functions and is involved in the regulation of multiple biological processes.FGL1 has an important role in the study of metabolic diseases,but further studies are needed to reveal its underlying mechanisms and the feasibility of clinical applications.This review is to summarize the role of FGL1 in the development and progression of DM,obesity,metabolic associated fatty liver disease and polycystic ovarian syndrome.