Expert consensus on aeromedical identification of vasogenic white matter hyperintensities in aircrews
10.11855/j.issn.0577-7402.0321.2025.0416
- VernacularTitle:飞行人员血管源性脑白质高信号航空医学鉴定专家共识
- Author:
Sheng-Yuan YU
;
Wen JIANG
- Collective Name:Expert consensus group on aeromedical identification of vasogenic white matter hyperintensities in Chinese aircrews
- Publication Type:Journal Article
- Keywords:
aircrew;
white matter hyperintensities;
magnetic resonance imaging;
medical assessment
- From:
Medical Journal of Chinese People's Liberation Army
2025;50(5):505-512
- CountryChina
- Language:Chinese
-
Abstract:
White matter hyperintensities(WMH)are abnormal high-signal manifestations in white matter areas on magnetic resonance T2-weighted or fluid-attenuated inversion recovery(FLAIR)sequences,with vasogenic WMH being the most common.Its pathological mechanism is related to cerebrovascular lesions and can lead to multi-dimensional brain functional impairments in cognition,movement,and emotions.Due to their unique working conditions,aircrews are more prone to vasogenic WMH than the general population.Moreover,with the widespread use of magnetic resonance imaging in cranial disease screening for aircrews,the detection rate of vasogenic WMH in aircrews has significantly increased.However,to date,no national or academic organization has issued standardized aviation medical assessment criteria for vasogenic WMH in aircrews.Therefore,led by Xijing Hospital of Air Force Medical University and the Chinese PLA General Hospital,a multi-disciplinary expert panel involved in aviation medicine,neurology,radiology,psychology,and related fields was assembled to formulate this consensus.The document integrates evidence from a systematic review of PubMed,CNKI,Wanfang Data,and VIP databases,incorporates existing WMH guidelines,and synthesizes clinical expertise from Chinese specialists.The consensus outlines three key domains:target population,neuroimaging protocols for vasogenic WMH screening,and clinical assessment and aeromedical identification for aircrews with vasogenic WMH.The aim is to provide evidence-based support and expert recommendations for standardizing and improving the accuracy of aviation medical evaluations of vasogenic WMH in aircrews.