Research advance of central nervous system infection in transplantation recipients
10.3760/cma.j.cn421203-20231220-00199
- VernacularTitle:器官移植受者中枢神经系统感染的研究进展
- Author:
Xingsong QIN
1
;
He ZHAO
1
;
Wei QIN
1
;
Hongyu WANG
1
Author Information
1. 河南中医药大学第五临床医学院器官移植中心 郑州人民医院，郑州 450003
- Publication Type:Journal Article
- Keywords:
Organ transplantation;
Central nervous system infection;
Pathogen
- From:
Chinese Journal of Organ Transplantation
2025;46(5):389-393
- CountryChina
- Language:Chinese
-
Abstract:
Recipients of organ transplants are prone to infection due to immunosuppressive agents. Compared to respiratory, urinary, and digestive system infection, central nervous system (CNS) infections exhibit lower incidence rates but carry poorer prognoses. Current epidemiological data remain limited, predominantly derived from case reports and single-center studies, with a notable absence of reliable diagnostic and therapeutic guidelines. This article comprehensively reviews domestic and international research and case reports on post-transplant CNS infection. From an etiological perspective, it elucidates the epidemiological and clinical characteristics of viral, bacterial, and fungal CNS infections, while summarizing diagnostic approaches and treatment strategies. The findings aim to provide clinical references for the management of central nervous system infection following organ transplantation.
