Mycobacterium tuberculosis associated with soft tissue Talaromyces marniffei infection after kidney transplantation: one case report
10.3760/cma.j.cn421203-20230906-00079
- VernacularTitle:肾移植术后结核分枝杆菌并软组织马尔尼菲蓝状菌感染1例
- Author:
Jinran YANG
1
;
Xinchang LI
1
;
Xiaoping HE
1
;
Gang LIU
1
;
Zehong FANG
1
Author Information
1. 江西省人民医院(南昌医学院第一附属医院)器官移植科,南昌 330000
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Mycobacterium tuberculosis;
Talaromyces marniffei;
Infection
- From:
Chinese Journal of Organ Transplantation
2024;45(12):903-906
- CountryChina
- Language:Chinese
-
Abstract:
It described the diagnosis and treatment of a kidney transplant recipient simultaneously infected with Mycobacterium tuberculosis and Talaromyces marniffei (TM). In early stage of treatment, this case was misdiagnosed as a single infection of Mycobacterium tuberculosis tuberculosis. However, anti-tuberculosis treatment was ineffective and general condition continued to deteriorate. Pathogenic examination yielded a definite diagnosis of skin and soft tissue infection caused by TM. The patient was cured with amphotericin B cholesterol sulfate complex, voriconazole and itraconazole successively while tapering the intensity of immunosuppressants. Transplanted kidney function normalized. There was no recurrence during a follow-up period of over 1 year.