Evaluation of Right Ventricular Function in Cardiac Amyloidosis by Two-Dimensional Speckle Tracking Imaging
10.3969/j.issn.1005-5185.2025.06.013
- VernacularTitle:二维斑点追踪成像技术评价心肌淀粉样变性患者右心室功能
- Author:
Huiying CHEN
1
;
Xiaojing MA
1
;
Juan XIA
1
;
Yafeng HE
1
;
Jingjing WANG
1
;
Jinlong ZHONG
1
Author Information
1. 武汉科技大学附属武汉亚洲心脏病医院超声科,武汉市心血管影像临床医学研究中心,湖北 武汉 430022;武汉科技大学医学部医学院,湖北 武汉 430065
- Publication Type:Journal Article
- Keywords:
Amyloidosis;
Cardiomyopathy,hypertrophic;
Echocardiography;
Speckle tracking imaging;
Ventricular function,right
- From:
Chinese Journal of Medical Imaging
2025;33(6):638-644
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of two-dimensional speckle tracking in evaluating right ventricular function in cardiac amyloidosis(CA).Materials and Methods A total of 25 patients with CA,30 patients with hypertrophic cardiomyopathy(HCM)and 30 healthy controls were retrospectively selected from July 2021 to October 2023 in Wuhan Asia Heart Hospital.The regional difference was represented by the formula apical ratio.The parameters of conventional echocardiography,two-dimensional strain and apical ratio of the three groups were analyzed and compared.Results Only segmental strain was different in right ventricular structure and function between CA group and HCM group,and the differences were statistically significant(all P<0.05).In the CA group,the strain gradient of the right ventricle from the apex of the heart to the base was the same as that of the left ventricle,that was,the"apex preservation"pattern,which was not seen in the HCM group and the control group.Comparison of the right ventricular free wall longitudinal strain-apical ratio,right ventricle four-chamber longitudinal strain-apical ratio,left ventride global longitudinal strain-apical ratio among the three groups,it was found that the levels of CA group were higher than HCM group and control group,and the differences were statistically significant(H=40.40,43.18,55.43,all P<0.05).The right ventricular free wall longitudinal strain-apical ratio had the highest CA recognition value,the area under the curve was 0.935,sensitivity was 96%and specificity was 83%.Conclusion Two-dimensional speckle tracking can accurately evaluate the right ventricular function impairment in CA patients and provide a new choice for clinical evaluation and identification of CA patients.
