Exploration of the Mechanism of Traditional Chinese Medicine in the Treatment of Alzheimer's Disease from the Perspective of Regulating Astrocytes
10.11842/wst.20240814003
- VernacularTitle:从调控星形胶质细胞角度探讨中药治疗阿尔茨海默病的机制
- Author:
Ziran ZHANG
1
;
Ziwei HU
;
Huiling TIAN
Author Information
1. 首都医科大学中医药学院 北京 100069
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
Astrocytes;
Energy metabolism;
Synaptic plasticity;
Neuroinflammation
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2025;27(6):1780-1785
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease(AD),a common geriatric ailment,exerts a severe impact on people's lives.Traditional Chinese medicine(TCM)demonstrates a favorable effect on the intervention of AD,while the mechanism remains in the exploratory phase.Recent studies have indicated that astrocytes play a significant role in AD.The mechanism of TCM in the treatment of AD from the perspective of astrocyte regulation was explored,and the roles of astrocytes in the pathogenesis of AD was summarized,namely maintaining energy metabolism,regulating synaptic plasticity,and mediating inflammatory responses,thereby providing a TCM-based solution with a clear mechanism for clinical and scientific intervention in AD.
