Role of Complement in the Development of Hypertensive Nephropathy
10.3969/j.issn.1000-3614.2025.03.017
- VernacularTitle:补体在高血压肾病发生发展中的作用
- Author:
Zhongli WANG
1
;
Tingting ZHANG
;
Xing WANG
;
Jianlong ZHAI
;
Lili HE
;
Qingjuan ZUO
;
Sai MA
;
Guorui ZHANG
;
Yifang GUO
Author Information
1. 河北省人民医院 体检中心,石家庄 050000
- Publication Type:Journal Article
- Keywords:
hypertensive nephropathy;
complement;
treatment
- From:
Chinese Circulation Journal
2025;40(3):308-312
- CountryChina
- Language:Chinese
-
Abstract:
Immunoinflammation mediates the development of hypertensive nephropathy,and aberrant activation of the complement system,an important component of the innate immune system,plays an important role in the development of hypertensive nephropathy.Complement inhibition is expected to be a potential strategy for the treatment of hypertensive nephropathy.In this article,we summarized and reviewed relevant studies on the complement system in the development of hypertensive nephropathy,and complement-targeted drug therapy,aiming to provide new ideas for clinicians on the clinical diagnosis and treatment of hypertensive nephropathy.
