Research progress on the role of a ketogenic diet in Parkinson's disease
10.3969/j.issn.1671-7856.2025.01.011
- VernacularTitle:生酮饮食在帕金森病领域的研究进展
- Author:
Boyang LI
1
;
Rui LAN
;
Huijie YANG
;
Hongyu LI
;
Chiyang LI
;
Xiaoming SHEN
Author Information
1. 河南中医药大学第一临床医学院,郑州 450000
- Publication Type:Journal Article
- Keywords:
ketogenic diet;
Parkinson's disease;
ketone bodies;
neuroprotection
- From:
Chinese Journal of Comparative Medicine
2025;35(1):111-118
- CountryChina
- Language:Chinese
-
Abstract:
A ketogenic diet(KD)refers to an eating pattern designed to achieve a low-calorie content,minimum carbohydrate intake,high-fat consumption,and standard protein levels.A ketogenic diet is used in clinical practice to treat conditions including heart disease,diabetes,obesity,autism,glioblastoma,and other cancers.Although a ketogenic diet has not been recommended for any neurological disorders except epilepsy,extensive recent research suggests that such a diet may have a neuroprotective effect and may thus represent a new dietary therapy for the treatment of Parkinson's disease(PD).In this review,we discuss in detail the mechanisms responsible for the neuroprotective effects of a ketogenic diet in Parkinson's disease,with the aim of providing references for future clinical and experimental studies.
