Research Progress on Pharmacological Mechanism of Ganoderma Lucidum Improving Cardiovascular Function
10.11842/wst.20240611003
- VernacularTitle:灵芝改善心血管功能的药理机制研究进展
- Author:
Xingyu FU
1
;
Jinchen LUO
;
Ting ZHU
;
Wenlan LI
Author Information
1. 哈尔滨商业大学药学院 哈尔滨 150076
- Publication Type:Journal Article
- Keywords:
Ganoderma lucidum;
Atherosclerosis;
Myocardial damage;
Anti-Inflammatory activity;
Antioxidant;
Mitochondrial dysfunction;
Regulate intestinal flora
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2025;27(6):1607-1615
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular diseases have the very high morbidity and mortality in the world.In recent years,the pharmacological effect and mechanism of Ganoderma lucidum has become the focus of research.Ganoderma lucidum,a traditional Chinese medicine,has broad development prospects and resource reserves.However,the mechanism of Ganoderma lucidum prevention and treatment of cardiovascular diseases is still lack of a complete review.In this paper,several domestic and foreign databases including CNKI and PubMed were searched to summarize the research progress of Ganoderma lucidum in anti-atherosclerosis,lowering blood lipids and lowering blood pressure in recent ten years.The main pharmacological mechanisms of Ganoderma lucidum in preventing and treating cardiovascular diseases include anti-inflammation,anti-oxidative stress,regulation of mitochondrial function,inhibition of calcium overload,regulation of intestinal flora and maintenance of cholesterol balance.On this basis.In addition,the paper also proposes to strengthen the in-depth study of Ganoderma lucidum in preventing and treating cardiovascular diseases,and pointed out the shortcomings of the existing research on Ganoderma lucidum,which provided some reference and guidance for promoting the in-depth study of its mechanism of action and clinical transformation of drugs.
