Advances in cerebral perfusion-guided blood pressure management in critically ill patients
10.3969/j.issn.1000-4718.2025.06.023
- VernacularTitle:脑灌注导向的重症患者血压管理的研究进展
- Author:
Leping FANG
1
;
Bo CHEN
1
;
Junjie LI
1
;
Zhigang WANG
1
Author Information
1. 暨南大学附属第一医院重症医学科,广东 广州 510632
- Publication Type:Journal Article
- Keywords:
critically ill patients;
blood pressure management;
cerebral perfusion
- From:
Chinese Journal of Pathophysiology
2025;41(6):1242-1248
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal cerebral perfusion impacts not only short-term brain function but may also cause irrevers-ible neurological deficits,significantly affecting patient prognosis.In intensive care units(ICU),patients often exhibit he-modynamic instability,intracranial pathologies,and impaired cerebrovascular autoregulation,which may result in cere-bral perfusion disorders,particularly cerebral hypoperfusion.Cerebral perfusion is determined by three key factors:blood pressure,intracranial pressure,and cerebrovascular regulatory function.Given that ICU patients have various types of un-derlying primary diseases,there is a need for unified standards regarding optimal blood pressure maintenance for all pa-tients and specific patient categories.Furthermore,cerebral perfusion-oriented blood pressure management requires indi-vidualized approaches for each patient.Therefore,the monitoring and integration of these parameters during ICU diagnos-tic and therapeutic processes are particularly crucial.
