Research Progress on Small Animal Models of Extracorporeal Membrane Oxygenation

VernacularTitle:小动物体外膜氧合模型的研究进展
Author: Hanying LIU ¹ ; Chunchao FAN ; Junyan GUO ; Hong CHEN ; Miao WANG
Author Information

1. 浙江师范大学生命科学学院,金华 321000;中国医学科学院北京协和医学院国家心血管病中心阜外医院心血管疾病国家重点实验室,北京 100037
Publication Type:Journal Article
Keywords: extracorporeal membrane oxygenation; small animal models; construct; application
From: Chinese Circulation Journal 2025;40(3):302-307
CountryChina
Language:Chinese
Abstract: Extracorporeal membrane oxygenation(ECMO)provides blood circulation with assisted breathing for patients with severe cardiopulmonary failure,and buys valuable time for the rescue of critical patients.However,extracorporeal membrane oxygenation is often associated with serious complications.Small animal models have the advantages of low price,wide source,high flexibility and good reproducibility,and are an effective platform for evaluating strategies for prevention and treatment of ECMO complications.In recent years,more and more experimental studies have been conducted using small animal ECMO models.In this paper,the current status of the construction and application of small animal ECMO models at home and abroad is summarized,in order to optimize the related strategies of small animal ECMO model construction and promote the application and development of small animal ECMO models.