Research progress in the protective mechanism of gut microbiota in radiation‐induced lung injury
10.3760/cma.j.cn113030-20240918-00362
- VernacularTitle:肠道菌群对放射性肺损伤的保护机制研究进展
- Author:
Shujun ZHANG
1
;
Xinmin DONG
;
Tiantian LI
;
Mingliang ZHONG
;
Wenjie WU
;
Mei JUN
;
Jian ZHANG
Author Information
1. 内蒙古医科大学第一临床医学院，呼和浩特 010059
- Publication Type:Journal Article
- Keywords:
Radiotherapy;
Radiation‐induced lung injury;
Gut microbiota;
Gut‐lung axis
- From:
Chinese Journal of Radiation Oncology
2025;34(8):819-823
- CountryChina
- Language:Chinese
-
Abstract:
Radiation‐induced lung injury (RILI) is one of the common and serious complications in chest cancer patients after undergoing radiotherapy. In recent years, gut microbiota has garnered attention as a research hotspot. Multiple studies found that it has preventive and therapeutic effects on RILI. It can exert its effects through various mechanisms including the regulation of the immune system, the gut‐lung axis and its own metabolites, etc. In this article, the mechanism of RILI was elucidated and the protective mechanism of gut microbiota against RILI was comprehensively analyzed, providing new insights for the prevention and treatment of RILI in clinical practice and offering new methods to improve patient prognosis and enhance the quality of life.
