Effect of 3D-printed headrest and multifunctional immobilization frame on radiotherapy dose in breast cancer
10.3760/cma.j.cn113030-20250320-00104
- VernacularTitle:3D打印头枕与多功能固定装置对乳腺癌放疗剂量的影响
- Author:
Yunpeng YIN
1
;
Zhao XIE
1
Author Information
1. 四川省医学科学院·四川省人民医院（电子科技大学附属医院）肿瘤中心，成都610072
- Publication Type:Journal Article
- Keywords:
Radiotherapy;
3D-printed immobilization device;
Dosimetric effect;
Breast neoplasms
- From:
Chinese Journal of Radiation Oncology
2025;34(12):1230-1237
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the dosimetric impact of 3D-printed headrests and multifunctional immobilization frames (MFIF) on hybrid radiotherapy plans for breast cancer patients, and to investigate the clinical significance of the attenuation effects.Methods:A retrospective analysis was conducted on 74 breast cancer patients who underwent radiotherapy at Sichuan Provincial People's Hospital between January and November 2024. Based on the segmentation results of immobilization device contours using the Mask2Former deep learning model, 4 body structure sets were generated for each patient, and 4 corresponding plans were created: original plan (P) and plans including MFIF (P _MF), 3D-printed headrests (P _3D), and a combination of these two (P _3D+MF). Dosimetric differences of supraclavicular target volumes (PTV up), chest wall target volumes (PTV down) and organ at risk (OAR) of these 4 plans were compared using paired t-test. Results:Compared with the P plan, the P _3D+MF plan reduced PTV up V 100% by 1.65% and D mean by 12.98 cGy ( P<0.001), while increasing PTV down homogeneity index (HI) by 3.11% ( P<0.001). Among OAR, the skin D mean was increased by 134.72 cGy ( P<0.001); left lung V 30 Gy was decreased by 0.22% ( P=0.004), right lung V 30 Gy, V 20 Gy, V 5 Gy, and D mean were decreased by 0.3%, 0.15%, 0.19%, and 3.33 cGy, respectively ( P=0.005, 0.001,<0.001, 0.004); while heart V 30 Gy, V 5 Gy, and D mean were increased by 0.67%, 0.21%, and 0.98 cGy, respectively ( P=0.001, 0.004, 0.010). Conclusions:The attenuation effects of 3D-printed headrests and MFIF significantly affect the dose distribution of target volumes and normal tissues. These effects should be incorporated into treatment planning optimization and dose calculation to improve the precision and safety of radiotherapy.
