Application exploration of bidirectional regulation among meridian,time rhythm,and immune system in allergic rhinitis
10.3969/j.issn.1006-2157.2025.06.014
- VernacularTitle:经络、时间节律、免疫系统双向调控在变应性鼻炎中的应用探讨
- Author:
Ke CHEN
1
;
Bowen XU
;
Xue LIANG
;
Di WU
;
Haoran XU
;
Jie ZHU
;
Jiabing TONG
;
Zegeng LI
Author Information
1. 安徽中医药大学第一附属医院 合肥 230031
- Publication Type:Journal Article
- Keywords:
meridian;
time rhythm;
immune system;
allergic rhinitis;
midnight-noon and ebb-flow doctrine
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(6):833-838
- CountryChina
- Language:Chinese
-
Abstract:
Time rhythm and the immune system play crucial roles in the pathogenesis of allergic rhinitis.Traditional Chinese medicine(TCM)believes that the circulation of qi and blood in lung meridian follows the principle of"yang during the day,yin at night",which has a defensive function to protect the body from external pathogens.Qi stagnation in lung meridian and impaired qi and blood circulation can lead to the invasion of external pathogens,exacerbating allergic reactions,especially during the active period of the lung meridian,when the immune system is most sensitive to allergens.Based on this,this paper proposes the concept of"bidirectional regulation among meridian,time rhythm,and immune system",and in combination with TCM theory of midnight-noon and ebb-flow doctrine,analyzes the fluctuations of allergic rhinitis symptoms and the temporal changes of meridian qi and blood,and reveals the rhythmic relationship between meridian activity and immune response.This paper combines existing clinical and experimental studies to support this hypothesis,integrating the time dimension into traditional TCM syndrome differentiation and treatment,offering a more individualized treatment approach.This concept not only provides novel scientific evidence for TCM treatment of allergic rhinitis,but also offers theoretical support for optimizing treatment timing and intervention strategies.
