Value of gemstone spectral CT multiparameter for risk assessment of acute pulmonary embolism
10.3969/j.issn.1002-1671.2025.06.012
- VernacularTitle:宝石光谱CT多参数对急性肺栓塞风险评估价值
- Author:
Lin ZHU
1
;
Mengmeng ZOU
;
Yuanyuan GAO
;
Na LÜ
;
Fei GUO
Author Information
1. 蚌埠医科大学第一附属医院放射科,安徽 蚌埠 233004;蚌埠医科大学医学影像学院,安徽 蚌埠 233004
- Publication Type:Journal Article
- Keywords:
gemstone spectral CT;
acute pulmonary embolism;
multiparameter;
risk assessment
- From:
Journal of Practical Radiology
2025;41(6):947-951
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of gemstone spectral CT multiparameter for risk assessment in acute pulmonary embolism(APE).Methods A total of 83 patients diagnosed with APE were categorized into three groups based on the European Society of Cardiology(ESC)guidelines:high-risk group(n=23),medium-high-risk group(n=29),and medium-low-risk group(n=31).The spectral CT multiparameters for each group were subsequently analyzed and compared.The predictive value of the region of interest perfusion defect iodine group value(ROI vPD),whole lung mean perfusion iodine group value(vMeanIP),and lung perfusion defect volume ratio(rPDvol)in high-risk APE patients were assessed using receiver operating characteristic(ROC)curves.Pearson correlation was employed to analyze the correlation of gemstone spectral CT multiparameter with pulmonary artery obstruction index(PAOI)and right ventricle/left ventricle diameter ratio(rRVD/LVD).Results Whole lung minimum perfusion iodine group value(vMinIP),whole lung maximum perfusion iodine group value(vMaxIP),vMeanIP,rPDvol and right ventricle/left ventricle volume ratio(rRVV/LVV)exhibited significant differences across all groups.The area under the curve(AUC)for ROI vPD,vMeanIP,and rPDvol in high-risk APE patients were 0.792,0.831,and 0.884,respectively.The sensitivity and specificity for ROI vPD(≤0.3),vMeanIP(≤1.1),and rPDvol(≥23.7％)were recorded at 95.7％and 60.0％,78.3％and 75.0％,as well as 91.3％and 75.0％,respectively.Simultaneously,the gemstone spectral CT multiparameter exhibited correlations with PAOI and rRVD/LVD.Conclusion The gemstone spectral CT multiparameter can be utilized to evaluate the severity and progression of patients with APE.
