Research advances in focal therapy for renal tumors
10.3969/j.issn.1009-8291.2025.11.008
- VernacularTitle:肾肿瘤局灶治疗的研究进展
- Author:
Shibo JIAN
1
;
Yin HUANG
1
;
Dehong CAO
1
;
Liangren LIU
1
Author Information
1. 四川大学华西医院泌尿外科/泌尿外科研究所,四川成都 610041
- Publication Type:Journal Article
- Keywords:
renal tumor;
focal therapy;
radiofrequency ablation;
cryoablation;
microwave ablation;
irreversible electroporation;
high-intensity focused ultrasound;
stereotactic ablative radiotherapy
- From:
Journal of Modern Urology
2025;30(11):955-959
- CountryChina
- Language:Chinese
-
Abstract:
Focal therapy has emerged as an alternative to surgical treatment for selected renal tumors.The core principle of this approach lies in the local destruction of tumor tissue through physical or chemical means to achieve tumor control.Focal therapy is particularly applicable to patients with tumors ≤4 cm in diameter who are unfit for surgery or anesthesia due to advanced age,comorbidities,solitary kidney,or renal insufficiency,as well as those with recurrent tumors after prior partial nephrectomy.This review summarizes the mechanisms,advantages,limitations,and clinical efficacy of six focal therapy modalities for renal tumors,including radiofrequency ablation,cryoablation,microwave ablation,irreversible electroporation,high-intensity focused ultrasound,and stereotactic ablative radiotherapy.The aim is to provide reference for achieving individualized and precise clinical management.
