Reflection on diagnosis and treatment of a case of sever Japanese spotted fever
10.3760/cma.j.issn.1674-2397.2025.04.007
- VernacularTitle:危重型日本立克次体感染1例诊疗分析与思考
- Author:
Xiangcheng DAI
1
;
Xiuwei YU
1
;
Honghu TAN
1
;
Qiang LIU
1
;
Xiaolin ZHOU
1
Author Information
1. 宜昌市中心人民医院感染性疾病科，宜昌 443003
- Publication Type:Journal Article
- Keywords:
Ricketttsia Japonica;
Dry gangrene;
Metagenomic next-generation sequencing;
Amputation
- From:
Chinese Journal of Clinical Infectious Diseases
2025;18(4):296-300
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore and summarize the key points and main treatment measures for successfully treating sever Rickettsia japonica infection. Methods:A 69-year-old female with severe Japanese spotted fever was admitted to Yichang Central People’s Hospital on May 15 in 2024 and was successfully treated. The clinical data of the patient were retrospectively analyzed.Results:The patient was quickly progressed to severe pneumonia，septic shock，dry gangrene of the extremities during the treatment process，and hepatic dysfunction，cardiac dysfunction，renal dysfunction and gastrointestinal hemorrhage were observed. After active anti-infection，anti-shock，continuous renal replacement therapy，and symptomatic supportive treatment，the patient’s condition improved，but the dry gangrene of the limbs was irreversible，ultimately leading to amputation.Conclusion:Timely diagnosis，early and active anti infective treatment，and effective management of various complications are the key to successfully treating cases of Ricketttsia Japonica
