Prevention and Treatment Principles of Virus-Associated Malignant Tumors under the Guidance of the"Cancer Toxin"Pathogenesis Theory
10.14148/j.issn.1672-0482.2025.1414
- VernacularTitle:癌毒病机理论指导下病毒相关恶性肿瘤的防治
- Author:
Hongli ZHOU
1
;
Luyu CHEN
;
Yuanyuan QIN
;
Wenting LI
;
Hongguang ZHOU
;
Mianhua WU
Author Information
1. 南京中医药大学第一临床医学院,江苏 南京 210023;江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
virus-associated malignant tumors;
cancer toxin;
immune evasion;
chronic inflammation;
preventive treatment of dis-ease
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(11):1414-1428
- CountryChina
- Language:Chinese
-
Abstract:
The development of malignant tumors is influenced by multiple factors,including genetics,environment,lifestyle,and pathogen infection.Viral infection plays a significant role in tumor development and progression.This article integrates the common pathways of seven oncogenic viruses(HPV,EBV,HBV,HCV,KSHV,HTLV-1,and HIV)based on the theory of cancer toxin pathomechanism.The findings reveal that cancer toxin formation is influenced by both internal factors(healthy qi deficiency,viscus dysfunction,and qi,blood,and body fluid stagnation)and external factors(viral infection,environmental factors,and the six exogenous pathogens),driving tumor development,metastasis,and recurrence.Viral infection not only provides the material foundation for cancer toxin but also accelerates its maturation and spread through chronic inflammation and immune imbalance,forming a complex pathogen-esis of"viral toxicity-endogenous cancer toxin",which translates into a three-stage strategy of"prevention,treatment,and post-recovery prevention".This article systematically discusses the pathogenesis of major cancer toxins and their associated tumors.Inte-grating the cancer toxin theory,the article explores preventive and therapeutic strategies for virus-associated malignancies,providing a theoretical basis and practical reference for the integrated prevention and treatment of tumors using traditional Chinese and Western medicine.
