Research progress in post-prostatectomy salvage radiotherapy for prostate cancer
10.3760/cma.j.cn113030-20241204-00465
- VernacularTitle:前列腺癌术后挽救性放射治疗研究进展
- Author:
Qiankun WANG
1
;
Minghuan LI
Author Information
1. 山东第一医科大学(山东省医学科学院)研究生部,济南 250117
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Radiotherapy, salvage;
Biochemical recurrence;
Prostate-specific antigen;
Androgen deprivation therapy
- From:
Chinese Journal of Radiation Oncology
2025;34(6):624-628
- CountryChina
- Language:Chinese
-
Abstract:
Over 40% of high-risk prostate cancer patients experience biochemical recurrence after radical prostatectomy. Salvage radiotherapy is the main therapeutic intervention for those with biochemical recurrence. To balance survival and quality of life, individual considerations are needed for the population benefiting from salvage radiotherapy, timing, whether to combine with androgen deprivation therapy, target volume, dose fractionation patterns, and adverse reactions. Currently, prostate-specific antigen related parameters are mainly used in clinics to guide salvage radiotherapy. In the future, the application of new functional molecular imaging technologies and genomic analysis of tissues, combined with traditional clinical and pathological parameters, could better assist clinical decision-making.