The Role of Traditional Chinese Medicine in Regulating Necroptosis to Prevent and Treat Respiratory Viral Infectious Diseases
10.14148/j.issn.1672-0482.2025.1493
- VernacularTitle:中药调控坏死性凋亡防治呼吸系统病毒感染性疾病
- Author:
Liping TAN
1
;
Yajun LI
;
Yan LIN
;
Lijie YIN
;
Xiuzhu WANG
;
Huan DOU
;
Yayi HOU
Author Information
1. 南京大学生命科学学院,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
necroptosis;
respiratory diseases;
viral infection;
cell death;
influenza virus;
rhinovirus;
respiratory syncytial virus
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(11):1493-1502
- CountryChina
- Language:Chinese
-
Abstract:
Infectious diseases of the respiratory system are very common in clinical practice,among which pneumonia caused by in-fluenza virus infection is characterized by high morbidity and mortality.Current clinical treatments for respiratory viral infections still face challenges such as drug resistance and poor efficacy.Necroptosis,a form of programmed cell death,is closely associated with the progression of respiratory viral infections.Traditional Chinese medicine modulating necroptosis has demonstrated beneficial therapeu-tic effects in these diseases.This paper introduces the concept and mechanisms of necroptosis,reviews recent research on the relation-ship between necroptosis and respiratory virus infections diseases,and summarizes the therapeutic effects of traditional Chinese medi-cine in regulating necroptosis to intervene in these diseases,aiming to provide insights for the development and clinical application of therapeutic agents for respiratory viral infections.
