Botulinum toxin type A for scar dancing syndrome:A case report
10.3969/j.issn.1002-0152.2025.10.006
- VernacularTitle:A型肉毒毒素治疗瘢痕舞蹈综合征1例
- Author:
Qing LIN
1
;
Jing LI
1
;
Weixi ZHANG
1
Author Information
1. 中山大学附属第一医院神经科(广州 510080)
- Publication Type:Journal Article
- Keywords:
Peripherally induced movement disorders;
Scar dancing syndrome;
Trauma;
Involuntary movements;
Piezo1 channel;
Botulinum toxin type A
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(10):615-617
- CountryChina
- Language:Chinese
-
Abstract:
Peripherally induced movement disorders are a rare in clinical practice.This study presents a case of scar-related chorea in a patient who developed abnormal movements under a surgical scar within one year following spinal surgery.The symptoms worsened with emotional excitement and partially improved when lying flat or sleeping,with no significant impact from voluntary movements or distraction.Examination revealed involuntary movements of the muscles beneath the scar.Brain magnetic resonance imaging demonstrated no remarkable structural abnormalities.The patient exhibited limited response to oral pharmacotherapy but achieved marked symptomatic improvement following botulinum toxin type A injection.Therapeutic effects persisted for approximately three months without adverse events.The underlying pathophysiology may involve abnormal activation of mechanically sensitive ion channel Piezo1 within the scar region.Botulinum toxin type A primarily alleviates symptoms by inhibiting muscle contraction and may also act indirectly by reducing mechanical stress-induced activation of Piezo1 channels.
