Preliminary Clinical Observation on the Implantation of AVEIR VR Single Chamber Leadless Pacemaker
10.3969/j.issn.1000-3614.2025.06.004
- VernacularTitle:AVEIR VR单腔植入式无导线心脏起搏器植入的初步临床观察
- Author:
Yi WEI
1
;
Feng ZE
1
;
Cuncao WU
1
;
Cuizhen YUAN
1
;
Ding LI
1
;
Xuebin LI
1
Author Information
1. 北京大学人民医院 心内科,北京 100044
- Publication Type:Journal Article
- Keywords:
leadless pacemaker;
AVEIR VR pacemaker;
real-world data;
pacing threshold
- From:
Chinese Circulation Journal
2025;40(6):577-582
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To evaluate the performance of AVEIR VR single chamber leadless pacemaker(AVEIR VR)in the real world in China and the predictive factors of pacing threshold to assess the feasibility of AVEIRTM VR implantation in the domestic population.Methods:All patients who underwent AVEIR VR implantation by experienced operators from Peking University People's Hospital in multiple domestic hospitals from June 2024 to October 2024 were consecutively included,and their baseline characteristics,procedural data(including pacemaker electrical measurements at various stages),and follow-up results were observed,recorded,and statistically analyzed.Results:This study included 20 patients who met the indication for pacemaker implantation and underwent AVEIR VR implantation.Their mean age was(71.40±13.37)years,body mass index(BMI)was(23.05±3.71)kg/m2,body surface area(BSA)was(1.70±0.16)m2,all 20 patients were successfully implanted with pacemakers,there were no major complications(newly occurred pericardial effusion during the perioperative period,cardiac tamponade,poor pacemaker function,pacemaker dislocation/perforation,tricuspid valve injury,myocardial infarction,stroke,pulmonary embolism,and clinical death).One patient developed new frequent ventricular premature contractions after pacemaker release.The pacing threshold(PCT)at one week after implantation was correlated with PCT in tether mode(r=0.650,P=0.009)and PCT in release phase(r=0.596,P=0.019),but not with the sensing and impedance in each phase.Conclusions:This preliminary exploration study show that AVEIRTM VR implantation demonstrates satisfactory performance among real world patients in China,especially in elderly and low weight populations,confirming its safety.
