Research progress in the role of lipid metabolism in radiotherapy for malignant tumors
10.3760/cma.j.cn113030-20240117-00018
- VernacularTitle:脂质代谢在恶性肿瘤放射治疗中的作用研究进展
- Author:
Qiliang PENG
1
;
Yuntian SHEN
1
;
Yaqun ZHU
1
;
Ye TIAN
1
Author Information
1. 苏州大学附属第二医院放疗科，苏州大学放射肿瘤学研究所，苏州 215004
- Publication Type:Journal Article
- Keywords:
Lipid metabolism;
Neoplasms, malignant;
Radiotherapy;
Radiosensitivity
- From:
Chinese Journal of Radiation Oncology
2025;34(2):206-210
- CountryChina
- Language:Chinese
-
Abstract:
Lipid metabolism plays a key role in tumorigenesis and progression and has a significant impact on the efficacy of radiotherapy. This article reviews the current research progress in the role of lipid metabolism in tumor radiotherapy, focusing on the central role of lipid metabolism in tumorigenesis, progression and metastasis, and how radiotherapy affects and regulates lipid metabolism. In addition, this article also investigates the intrinsic link between lipid metabolism and tumor radiosensitivity, and reviews how lipid metabolism can be used as a therapeutic strategy to improve the efficacy of radiotherapy. In-depth study of the role of lipid metabolism in tumor radiotherapy may offer assistance for clinical trials and mechanistic studies of tumor radiotherapy based on the modulation of lipid metabolism.
