A study of resting-state functional MRI degree centrality in patients with benign paroxysmal positional vertigo
10.3969/j.issn.1002-1671.2025.11.001
- VernacularTitle:良性阵发性位置性眩晕患者静息态功能MRI度中心性的研究
- Author:
Yu HAN
1
;
Xiaolian XU
;
Shanshan GAO
;
Zihao MU
;
Zhaoshun WANG
;
Jingang LIU
;
Xizhen WANG
;
Yue GUAN
Author Information
1. 山东第二医科大学附属医院医学影像中心,山东 潍坊 261031
- Publication Type:Journal Article
- Keywords:
benign paroxysmal positional vertigo;
degree cen-trality;
multiband;
resting-state functional magnetic resonance imaging
- From:
Journal of Practical Radiology
2025;41(11):1765-1768
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the abnormal changes characteristics of the degree centrality(DC)of the brain functional network in patients with benign paroxysmal positional vertigo(BPPV)in the classical frequency band(0.010-0.080 Hz),the slow-4 frequency band(0.027-0.073 Hz),and the slow-5 frequency band(0.010-0.027 Hz).Methods Twenty patients with BPPV(BPPV group)and 14 healthy controls(HC)(HC group)were selected.Resting-state functional magnetic resonance imaging(rs-fMRI)scans were performed,and the clinical data were analyzed.The DC method was used to analyze the changes of centrality of resting state network in patients with BPPV.Results Compared with the HC group,the BPPV group showed an increase in DC in the left caudate nucleus in the classical frequency band(P＜0.05),and a decrease in DC in the right auxiliary motor region in the classical frequency band(P＜0.05);within the slow-4 frequency band,no significant differences were observed in brain regions(P＞0.05);within the slow-5 frequency band,the BPPV group showed an increase in DC in the left thalamus(P＜0.05),while the left anterior cingulate and paracingulate gyrus showed a decrease in DC(P＜0.05).Conclusion Patients with BPPV have spontaneous activity disorders in multiple brain regions at resting states,and these changes show frequency band specificity.
