Research progress on radiotherapy in breast cancer patients with BRCA gene mutations
10.3760/cma.j.cn113030-20240625-00249
- VernacularTitle:BRCA基因突变乳腺癌患者放疗的研究进展
- Author:
Jiarong LIU
1
;
Shulian WANG
1
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科，北京 100021
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
BRCA gene;
Radiotherapy;
Prognosis
- From:
Chinese Journal of Radiation Oncology
2025;34(4):389-394
- CountryChina
- Language:Chinese
-
Abstract:
Women carrying BRCA gene mutations have a higher lifetime risk of developing breast cancer compared to non-carriers. Radiotherapy, as a key treatment for breast cancer, is typically applied after breast-conserving surgery or mastectomy. In this review, we summarize recent literature to evaluate the efficacy of different local treatment approaches for early-stage breast cancer in BRCA mutation carriers, as well as adverse effects associated with radiotherapy, thus providing valuable insights for clinical decision-making in BRCA mutation carriers.
