Progress on novel vascular endothelial injury markers in cardiovascular diseases
10.20039/j.cnki.1007-3949.2025.05.012
- VernacularTitle:新型血管内皮损伤标志物在心血管疾病中的研究进展
- Author:
Yifei XU
1
;
Hong WU
1
Author Information
1. 海军军医大学第一附属医院心血管内科,上海市 200433
- Publication Type:Journal Article
- Keywords:
biomarkers;
endothelial cell;
cardiovascular diseases;
endothelial cell specific molecule-1
- From:
Chinese Journal of Arteriosclerosis
2025;33(5):455-460
- CountryChina
- Language:Chinese
-
Abstract:
Aim Biomarkers of vascular endothelial injury serve as crucial indicators for assessing vascular endo-thelial function and provide a basis for the diagnosis and treatment of cardiovascular diseases(CVD).Currently,the mechanisms and clinical significance of classical biomarkers,such as C-reactive protein and intercellular adhesion mole-cule,in CVD have been extensively studied.However,their limited sensitivity and specificity make it difficult to compre-hensively reflect the progression of CVD.With the advancement of liquid biopsy and novel molecular biology detection technologies,emerging biomarkers of vascular endothelial injury have become a research focus.This article systematically reviews biomarkers of vascular endothelial injury,with a particular emphasis on the research progress and clinical applica-tions of novel biomarkers in CVD.
