Effects of typical persistentorganic pollutants on atherosclerosis
10.20039/j.cnki.1007-3949.2025.05.011
- VernacularTitle:典型持久性有机污染物对动脉粥样硬化的影响
- Author:
Yijia KE
1
;
Rui XU
;
Zhenzhen TAN
;
Junli LYU
;
Mingmei GUO
;
Zhengyi SU
;
Huicai GUO
Author Information
1. 河北医科大学公共卫生学院毒理学教研室
- Publication Type:Journal Article
- Keywords:
persistent organic pollutants;
atherosclerosis;
cardiovascular disease
- From:
Chinese Journal of Arteriosclerosis
2025;33(5):447-454
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease is one of the serious health burdens in the world,and atherosclerosis is its impor-tant pathological basis.In recent years,the effect of environmental pollutants on human health has been paid more and more attention.Some new epidemiological studies and experiments have reported that environmental organic pollutants,involved in the occurrence and development of atherosclerosis,is an independent risk factor of cardiovascular diseases.Evidence shows that it is related to oxidative stress response,cell phenotype transformation,dyslipidemia,genetic changes and so on.This review summarizes available studies on the latest epidemiological studies and experiments of typical per-sistent organic pollutants such as polychlorinated biphenyls and per-and polyfluoroalkyl substances so as to provide refer-ences for future research.
