Transcatheter edge-to-edge repair strategies for mitral commissural prolapse: a single-center experience
- VernacularTitle:经导管二尖瓣缘对缘修复术在交界脱垂解剖患者中应用策略的单中心经验
- Author:
Xinping LIN
1
;
Wangxing HU
1
;
Qifeng ZHU
1
;
Huajun LI
1
;
Jie LIANG
1
;
Huixiang YAN
1
;
Lihan WANG
1
;
Po HU
1
;
Jubo JIANG
1
;
Kaida REN
1
;
Jiaqi FAN
1
;
Yuxin HE
1
;
Xianbao LIU
1
;
Jian'an WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Mitral valve prolapse; Mitral valve regurgitation; Transcatheter edge-to-edge repair; Commissural
- From: Chinese Journal of Cardiology 2025;53(4):356-362
- CountryChina
- Language:Chinese
- Abstract: Objective:To investigate the feasibility of transcatheter edge-to-edge repair (TEER) using a short-clip strategy for patients with moderate-to-severe or greater degenerative mitral regurgitation caused by commissural prolapse.Methods:This retrospective study included patients with severe mitral regurgitation secondary to commissural prolapse who underwent TEER at the Second Affiliated Hospital of Zhejiang University School of Medicine between September 2022 and July 2024. Preoperative clinical and imaging data, intraoperative details, procedural outcomes, and 1-month postoperative follow-up results were collected.Results:A total of 19 patients were enrolled, aged (74.1±6.1) years, including 12 males. Among them, 10 patients had external commissural prolapse, and 9 patients had internal commissural prolapse. Preoperatively, all patients exhibited severe mitral regurgitation (4+), with an effective regurgitant orifice area of (0.55±0.17) cm2, left atrial volume of (104.77±36.57) ml, left ventricular end-diastolic volume of (102.29±32.47) ml, left ventricular end-diastolic dimension of (5.34±0.59) mm, and prolapse width of (1.18±0.34) cm. All procedures utilized short clips (NTR or NTW clips) to target the prolapsed commissural region and were completed successfully without intraoperative complications. At 1-month follow-up, no mortality, stroke, single-leaflet device attachment, myocardial infarction, or unplanned mitral reintervention occurred. Mitral regurgitation severity improved to ≤2+ in all patients, with left atrial volume of (74.49±33.83) ml, left ventricular end-diastolic volume of (85.90±18.05) ml, and left ventricular end-diastolic dimension of (4.93±0.37) mm (all P<0.05). Conclusion:The short-clip strategy, focusing on precise clip placement at the commissural interface, is feasible and effective for TEER in patients with severe mitral regurgitation due to commissural prolapse.
