Research progress of exosomal non-coding RNA in diabetes and its complications
10.3969/j.issn.1006-6187.2025.06.014
- VernacularTitle:外泌体非编码RNA在糖尿病及其并发症中的研究进展
- Author:
Xinxin HU
1
;
Limin TIAN
Author Information
1. 730000 兰州大学第一临床医学院
- Publication Type:Journal Article
- Keywords:
Exosomes;
Non-coding RNA;
Diabetes mellitus;
Complication
- From:
Chinese Journal of Diabetes
2025;33(6):476-480
- CountryChina
- Language:Chinese
-
Abstract:
The high incidence of diabetes mellitus(DM)and its chronic complications imposed a heavy burden on families and society,yet the specific mechanism remain unclear.Exosomal non-coding RNA(ncRNA)is involved in various mechanisms of DM pathogenesis,playing a crucial role in the autoimmune process of type 1 diabetes mellitus and the development of insulin resistance and β-cell dysfunction in type 2 diabetes mellitus.Exosomal ncRNA shold potential for improving DM and its complications,particularly those derived from mesenchymal stem cell.This article reviews the research on exosomal ncRNA in DM and its complications.
