Evaluation of non-human primate anatomical operation risk assessment and control measures in high-level biosafety laboratories
- VernacularTitle:高级别生物安全实验室非人灵长类解剖操作风险评估与控制措施探究
- Author:
Xiaoqi ZHENG
1
;
Senren XUE
1
;
Xianyu ZHANG
1
;
Jiaxin YANG
1
;
Yuyu CHEN
1
;
Xiaobo LI
1
;
Jingwen LIN
1
;
Yabin ZHANG
1
;
Jianbao HAN
1
Author Information
- Publication Type:Journal Article
- Keywords: high-level biosafety laboratory; non-human primate; animal dissection; risk assessment; control measures
- From: Chinese Journal of Comparative Medicine 2025;35(10):69-78
- CountryChina
- Language:Chinese
- Abstract: Non-human primate animal models are core tools for the study of highly pathogenic microorganisms and are irreplaceable in the fields of pathology and drug discovery.However,anatomical sampling of non-human primate infection models in high-level biosafety laboratories carries potential risk and related risk assessment and control measures require clarification.Based on biosafety regulations and practical experience,we systematically discuss the risk control strategies of anatomical operations with respect to personal protection,instrument selection,anatomical specifications,documentation,and personnel training.Our review will help to improve the management of high-level biosafety laboratories,reduce the risk of pathogen escape and human infection,and provide support for the safe research of highly pathogenic microorganisms.
