Research advances in disease burden and prevention of respiratory syncytial virus infections in preterm infants
10.3760/cma.j.cn113903-20250831-00481
- VernacularTitle:早产儿呼吸道合胞病毒感染疾病负担与防治研究进展
- Author:
Jianyu FENG
1
;
Shushu LI
1
;
Shuping HAN
1
;
Miao QIAN
1
Author Information
1. 南京医科大学附属妇产医院（南京市妇幼保健院）儿科，南京 210004
- Publication Type:Journal Article
- Keywords:
Respiratory syncytial virus;
Preterm infant;
Disease burden;
Treatment;
Prevention
- From:
Chinese Journal of Perinatal Medicine
2025;28(12):1071-1076
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory syncytial virus (RSV) represents the leading viral pathogen causing acute lower respiratory infections in children under five years worldwide. Preterm infants, due to their immature immune systems and pulmonary development, along with frequent comorbidities such as bronchopulmonary dysplasia, constitute a high-risk population for RSV infections. Globally, RSV infections in preterm infants impose substantial burdens across clinical, economic, and long-term health dimensions. Current prevention and treatment options remain limited, primarily relying on supportive care as no specific antiviral drugs are available, while preventive strategies encompass general measures and specific interventions including monoclonal antibodies and RSV vaccines. This review synthesizes recent advances in understanding RSV susceptibility, disease burden, and prevention strategies in preterm infants, aiming to enhance awareness and provide references for managing RSV infections in this vulnerable population.
