Advances in early recognition and management of severe respiratory syncytial virus infections in neonates
10.3760/cma.j.cn113903-20250331-00156
- VernacularTitle:新生儿重症呼吸道合胞病毒感染的早期识别及防治进展
- Author:
Pu XU
1
;
Ying CHEN
;
Yajuan WANG
Author Information
1. 首都儿科研究所，北京协和医学院，中国医学科学院，北京 100020
- Publication Type:Journal Article
- Keywords:
Respiratory syncytial virus;
Infant, newborn;
Severe disease;
Early diagnosis;
Prevention
- From:
Chinese Journal of Perinatal Medicine
2025;28(12):1065-1070
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory syncytial virus (RSV) is the primary pathogen causing acute lower respiratory tract infections in neonates. Since the adjustment of COVID-19 prevention policies in December 2022, RSV infection rates have increased among children in multiple regions. Neonates' immature immune systems render them particularly vulnerable, with preterm infants facing higher infection risks than term infants, and severe cases potentially progressing to acute respiratory failure. Currently, no specific antiviral therapy exists for RSV, with management relying primarily on supportive care. This review synthesizes current knowledge on RSV epidemiology, risk factors for severe disease, early clinical recognition, diagnosis, treatment, and prevention strategies, providing clinical guidance for early identification and management of severe RSV infections in neonates.
