Discussion on the pathogenesis evolution of cerebral small vessel disease related to brain aging based on the rhythm of qi
10.3969/j.issn.1006-2157.2025.07.014
- VernacularTitle:基于气之节律探讨脑衰老相关脑小血管病的病机演变
- Author:
Lili SHAN
1
;
Cen GUO
;
Yan HAN
;
Yongyan WANG
Author Information
1. 上海中医药大学附属岳阳中西医结合医院 上海 200080
- Publication Type:Journal Article
- Keywords:
qi;
rhythm;
cerebral small vessel disease;
pathogenesis
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(7):985-991
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease is a group of age-related pathological syndromes with complex and diverse clinical symptoms.In the early stage,it is often asymptomatic or manifested as sleep or emotional disorders.Further disease development can lead to stroke or dementia,making it a crucial target for the early prevention and treatment of brain aging.Studies have shown that biological rhythm disorders are significantly associated with the onset,progression,and outcome of cardiovascular and cerebrovascular diseases.With the rapid development of modern society,the fast-paced lifestyle leads to the disorder of the body′s biological rhythm,thereby accelerating the aging process.However,few studies have investigated the correlation between cerebral small vessel disease and biological rhythm disorders in Western medicine.Sleep disorders and increased blood pressure variability related to cerebral small vessel disease may represent specific manifestations of biological rhythm disorders.The pathogenesis of cerebral small vessel disease is related to qi collaterals,and the biological rhythm disorder is mainly caused by the disorder of the growth and decline of yin and yang qi and the circulation of nutrient qi and defensive qi in the human body.Therefore,the disorder of qi rhythm may be involved in the early pathological mechanism of cerebral small vessel disease.By integrating Western medical research,this article explores the evolution of traditional Chinese medicine pathogenesis of cerebral small vessel disease associated with brain aging from the perspective of qi rhythm,aiming to provide novel diagnostic and treatment insights for the clinical treatment of cerebral small vessel disease.
