Impacts of hyperglycemia in pregnancy on offspring cardiovascular health and underlying mechanisms: advances in research

VernacularTitle:妊娠期高血糖对子代心血管健康的影响及机制研究进展
Author: Ruiqi SUN ¹ ; Guoying HUANG
Author Information

1. 复旦大学附属儿科医院心血管中心，上海　201102
Publication Type:Journal Article
Keywords: Hyperglycemia in pregnancy; Offspring; Cardiovascular health; Mechanism
From: Chinese Journal of Perinatal Medicine 2025;28(11):985-988
CountryChina
Language:Chinese
Abstract: Hyperglycemia in pregnancy (HIP) exerts profound adverse effects on fetal development. While fetal cardiovascular abnormalities involve genetic and environmental factors, HIP serves as a critical environmental determinant that disrupts cardiovascular development through multiple pathways. These disruptions can lead to structural malformations, functional impairments, and long-term cardiovascular consequences in adulthood. Therefore, understanding HIP's impacts on offspring cardiovascular health and elucidating the underlying mechanisms are crucial.