Exploring the research paradigm of"disease-syndrome-prescription"in traditional Chinese medicine based on the formula-syndrome scientific connotation of Xiaoyao Powder
10.3969/j.issn.1006-2157.2025.07.001
- VernacularTitle:基于逍遥散方证科学内涵探讨中医"病-证-方"的研究范式
- Author:
Wenzhi HAO
1
;
Xiaojuan LI
;
Feifei XUE
;
Jiaxu CHEN
Author Information
1. 暨南大学中医学院,广州市中医方证重点实验室 广州 510632
- Publication Type:Journal Article
- Keywords:
integration of disease and syndrome;
correlation between syndrome and prescription;
syndrome differentiation and treatment;
research paradigm
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(7):889-895
- CountryChina
- Language:Chinese
-
Abstract:
As the defining characteristic and essence of traditional Chinese medicine(TCM),the integration of disease and syndrome,along with the correlation between syndrome and prescription,forms the foundation for syndrome differentiation and treatment,and guides the clinical diagnosis and treatment practice of TCM.However,key scientific questions remain unresolved regarding the"disease-syndrome-prescription"framework,particularly the biological basis of diseases and syndromes,the active pharmacodynamic constituents of compound formulas,and their mechanism of action.Furthermore,a systematic paradigm for investigating"disease-syndrome-prescription"relationships has not been established,restricting the innovation and development of TCM theory and practice.Xiaoyao Powder,which was first described in a medical book named Taiping Huimin Heji Ju Fang written during the Song Dynasty of China,disperses stagnated liver qi for relieving qi stagnation,thus nourishing the blood and strengthening the spleen,making it a representative prescription for addressing depression due to liver qi stagnation and spleen deficiency under the guidance of correspondence between syndrome and prescription.Therefore,base on the combination of disease and syndrome,and correspondence between syndrome and prescription,investigating the formula-syndrome scientific connotation of Xiaoyao Powder and exploring the research paradigm for the"disease-syndrome-prescription"can provide insights into TCM theory from the perspective of modern science.
