Clinical research progress of neonatal acute respiratory distress syndrome
10.3760/cma.j.cn113903-20250114-00024
- VernacularTitle:新生儿急性呼吸窘迫综合征临床研究进展
- Author:
Chongxun ZHANG
1
;
Zheng LI
1
;
Xiangyu GAO
1
Author Information
1. 徐州市中心医院（徐州医科大学徐州临床学院）新生儿科，徐州 221009
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome, acute;
Diagnosis;
Treatment;
Infant, newborn
- From:
Chinese Journal of Perinatal Medicine
2025;28(8):711-715
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal acute respiratory distress syndrome (ARDS) is a clinical condition characterized by acute respiratory failure with refractory hypoxemia triggered by local or systemic etiologies during the neonatal period. Diagnosis primarily relies on the Montreux criteria. Oxygen index is recommended for grading index and lung ultrasound scoring is recommended for auxiliary diagnosis and treatment index. Current therapeutic strategies include high-frequency oscillatory ventilation, high-dose pulmonary surfactant administration, inhaled nitric oxide, intratracheal instillation of budesonide combined with surfactant, prone positioning, extracorporeal membrane oxygenation. Despite these interventions, targeted therapies remain limited. In particular, neonates with moderate or severe neonatal ARDS generally carry a poor prognosis, with mortality escalating in severe cases or those with systemic etiologies.
