Effectiveness of implementing a single-disease quality management approach in the hospital infection control department for antibiotic management
10.3969/j.issn.1672-8467.2025.04.004
- VernacularTitle:医院感染管理科利用单病种质量管理推进抗菌药物管理的成效
- Author:
Rui CHANG
1
;
Xiang CHEN
;
He-feng YIN
;
Ren ZHU
Author Information
1. 上海市肺科医院院感科 上海 200433
- Publication Type:Journal Article
- Keywords:
single-disease management;
antibiotic;
use intensity
- From:
Fudan University Journal of Medical Sciences
2025;52(4):500-505,512
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a precise and efficient single-disease management model to reduce the intensity of antibiotic use.Methods Data was collected from surgical inpatient admissions at the Shanghai Pulmonary Hospital between Jan 2022 and Mar 2024.The study focused on the six most prevalent types of malignant tumors within single-disease management.Surgical patients who did not receive single-disease quality management from Jan 2022 to Jun 2023 were designated as the control group,while surgical patients who received single-disease quality management from Jul 2023 to Mar 2024 served as the management group.By formulating and implementing standardized policies and guidelines for antibiotic use,supervision and effect evaluation were conducted across departments.Results A total of 21 746 individuals were included in the control group and 15 635 in the management group.Following the introduction of the single-disease management model,the proportion of non-restricted antibiotics used in various single diseases increased from 73.2%-77.0%before management to 78.3%-84.4%after management,while the usage of restricted antibiotics significantly decreased(P<0.001).The intensity of antibiotic use,measured in defined daily doses(DDDs),fell significantly from 113.0-159.9 before management to 36.0-44.0 after management(P<0.001).Moreover,compared with the control group,the average length of stay in the intervention group did not change considerably,although the length of stay increased for some diseases,possibly due to more precise medication adjustments.Conclusion The single-disease management model optimizes antibiotic use,reduces the intensity of antibiotic use,and enhances overall medical quality and patient safety.
