Summary of best evidence for management strategies of perinatal intraventricular hemorrhage in preterm infants
10.3760/cma.j.cn113903-20250311-00111
- VernacularTitle:围产期早产儿脑室内出血管理策略的最佳证据总结
- Author:
Fei SHEN
1
;
Hui RONG
;
Rui CHENG
;
Banghong XU
;
Mengya YU
;
Zhouxuan HUANG
;
Yang YANG
;
Xianwen LI
Author Information
1. 南京医科大学附属儿童医院新生儿医疗中心,南京 210008
- Publication Type:Journal Article
- Keywords:
Preterm infant;
Intraventricular hemorrhage;
Perinatal period;
Management;
Evidence-based nursing
- From:
Chinese Journal of Perinatal Medicine
2025;28(10):873-882
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To integrate the best available evidence regarding the management of perinatal intraventricular hemorrhage (IVH) in preterm infants.Methods:Using keywords such as "intracranial hemorrhage", "intraventricular hemorrhage", "germinal matrix hemorrhage", and their Chinese equivalents, we systematically searched for clinical decisions, guidelines, expert consensuses, evidence summaries, group standards, systematic reviews, and meta-analyses related to IVH management in preterm infants. Data sources included BMJ Best Practice, UpToDate, World Health Organization website, Guidelines International Network, National Institute for Health and Care Excellence, Scottish Intercollegiate Guidelines Network, Registered Nurses' Association of Ontario, National Guideline Clearinghouse, American Academy of Pediatrics, Canadian Paediatric Society, European Foundation for the Care of Newborn Infants, British Association of Perinatal Medicine, Yiigle, Cochrane Library, Joanna Briggs Institute, PubMed, Web of Science, CINAHL, MEDLINE, Embase, China National Knowledge Infrastructure, Wanfang Data, and SinoMed. The search period spanned from January 2015 to December 2024. Literature screening, quality appraisal, evidence extraction, and synthesis were performed independently according to uniform standards.Results:A total of 12 publications were included, comprising three clinical decisions, three evidence-based guidelines, and six expert consensuses. Thirty-seven best evidence statements were synthesized across four domains: risk factor identification, diagnosis and monitoring, antenatal and delivery room management, and neonatal intensive care unit management. These included 28 strong recommendations (Grade A) and nine weak recommendations (Grade B).Conclusion:The 37 summarized best evidence statements provide an evidence-based foundation for developing clinical management protocols for perinatal IVH in preterm infants.