Latest Application Research Progress of Gas Chromatography-Mass Spectrometry Analysis Technology in the Field of Laboratory Medicine
10.3969/j.issn.1671-7414.2025.04.039
- VernacularTitle:气相色谱-质谱联用分析技术在检验医学领域的最新应用研究进展
- Author:
Zhizheng LI
1
;
Zhonggan JIN
Author Information
1. 上海健康医学院医学技术学院,上海 201318
- Publication Type:Journal Article
- Keywords:
gas chromatography-mass spectrometry;
clinical laboratory medicine;
biomarker
- From:
Journal of Modern Laboratory Medicine
2025;40(4):214-220
- CountryChina
- Language:Chinese
-
Abstract:
Gas chromatography-mass spectrometry(GC-MS)technology has the characteristics of high sensitivity,high specificity and wide range of applications,and it has been widely used as a routine tool for disease screening and diagnosis in the field of clinical laboratory medicine.Since its introduction,GC-MS has been widely adopted in clinical laboratories over the years,enabling the detection of various substances in areas such as prenatal screening,genetic metabolic disorders and metabolomics.This paper primarily reviews the features of GC-MS technology and its applications in clinical laboratory medicine,aiming to highlight the indispensable role of GC-MS.It also discusses how GC-MS can complement the widely used liquid chromatography-tandem mass spectrometry(LC-MS)technology,thereby supporting further clinical research and application of GC-MS.
