Latest Advances in Nanopore Sequencing Technology in Molecular Biology and Molecular Medicine
10.3969/j.issn.1671-7414.2025.04.038
- VernacularTitle:纳米孔测序技术在分子生物学和分子医学研究的最新进展
- Author:
Mengke ZHAO
1
;
Yao HAN
;
Yansong SUN
;
Haiyan YANG
;
Hao LI
Author Information
1. 郑州大学公共卫生学院,郑州 450001;军事医学研究院微生物流行病研究所,北京 100071
- Publication Type:Journal Article
- Keywords:
nanopore sequencing;
third-generation sequencing technology;
molecular biology
- From:
Journal of Modern Laboratory Medicine
2025;40(4):208-213
- CountryChina
- Language:Chinese
-
Abstract:
Nanopore sequencing,as a representative of third-generation sequencing technology,is widely used in molecular biology research.It offers several advantages,including high throughput,ultra-long read lengths,real-time sequencing,and the absence of amplification and labeling requirements.This technology has been applied for the detection of various pathogens,genomic typing,structural variation analysis,and personalized treatment guidance,making it valuable for pathogen monitoring and medical research.This article focuses on the principles of nanopore sequencing technology,its advantages,and its applications in molecular biology and molecular medicine.The limitations of nanopore sequencing and its future development directions are also summarized,providing new perspectives for further research in this field.
