Research progress on breast milk improving brain damage and neurodevelopment in preterm infants
10.3969/j.issn.1672-8467.2025.04.017
- VernacularTitle:母乳改善早产儿脑损伤和神经发育的研究进展
- Author:
Ling ZHAO
1
;
Lai-shuan WANG
1
Author Information
1. 国家儿童医学中心/复旦大学附属儿科医院新生儿诊疗中心 上海 201102;国家卫生健康委员会新生儿疾病重点实验室 上海 201102
- Publication Type:Journal Article
- Keywords:
breast milk;
preterm infants;
brain injury;
neurodevelopment
- From:
Fudan University Journal of Medical Sciences
2025;52(4):589-595
- CountryChina
- Language:Chinese
-
Abstract:
With the continuous development of perinatal medicine and neonatology,although the survival rate of infants with low gestational age and low birth weight has improved,the incidence of neurodevelopmental morbidities remains high.Breast milk is the preferred source of enteral nutrition for preterm infants,playing an important role in growth,development,immunity,metabolism,and other functions.Of particular note is its effect on the nervous system,not only promoting brain development and maturation in preterm infants,but also effectively reducing the incidence and severity of brain injury,thereby improving long-term neurological outcomes.This review aims to explore the effects of breast milk on brain injury and repair,brain structural maturation,and neurodevelopmental outcomes in preterm infants,in order to further enhance the understanding of the importance of breast milk for the neurodevelopment of preterm infants.