Fetal intracranial toxoplasmosis: MRI findings in a case report

VernacularTitle:胎儿颅内弓形虫感染MRI表现1例
Author: Yan SONG ¹ ; Yunlu MO ; Hongbo PU ; Hongyu YIN ; Xi CHEN ; Qiyan WANG ; Yangmei PU ; Min KANG
Author Information

1. 四川省妇女儿童医院（成都医学院附属妇女儿童医院）放射科，成都　610000
Publication Type:Journal Article
Keywords: Toxoplasmosis; Magnetic resonance imaging; Prenatal diagnosis
From: Chinese Journal of Perinatal Medicine 2025;28(10):899-901
CountryChina
Language:Chinese
Abstract: Toxoplasmosis is a zoonotic disease caused by infection with Toxoplasma gondii. Congenital toxoplasmosis is a common form of intrauterine infection and is associated with severe neurological sequelae such as cerebral palsy and cognitive impairment. This report presented the magnetic resonance imaging (MRI) features of a fetal intracranial toxoplasmosis case, including bilateral ventriculomegaly, multiple intracranial cystic lesions, and parenchymal calcifications, without concurrent retinal abnormalities or hepatosplenomegaly. Post-termination analyses confirmed the presence of T.gondii DNA in amniotic fluid and umbilical venous blood, with histopathology revealing necrosis and eosinophilic infiltration. MRI demonstrates superior soft-tissue resolution in evaluating the extent of cerebral lesions and parenchymal damage, underscoring its diagnostic value in fetal toxoplasmic encephalopathy.