Prevalence and influencing factors of chronic somatic comorbidities in patients with schizophrenia in Shanghai communities
10.3969/j.issn.1672-8467.2025.04.002
- VernacularTitle:上海市社区精神分裂症患者共病慢性躯体疾病的状况及影响因素分析
- Author:
Wei-bo ZHANG
1
;
Jiang-nan LI
;
Yan-li LIU
;
Yi-zhou JIANG
;
Yi ZHU
;
Na WANG
;
Jun CAI
Author Information
1. 上海交通大学医学院附属精神卫生中心防治科 上海 200030;上海市精神卫生中心浦江医院院长办公室 上海 201112;上海市闵行区精神卫生中心院长办公室 上海 201112
- Publication Type:Journal Article
- Keywords:
schizophrenia(SCZ);
somatic diseases;
comorbidity;
community psychiatry
- From:
Fudan University Journal of Medical Sciences
2025;52(4):484-491,499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of chronic somatic comorbidities in schizophrenic patients in Shanghai communities,and to explore the factors influencing comorbidities.Methods Based on Shanghai community-based severe mental disorders cohort,5 422 patients with schizophrenia(SCZ)were included in the study.12 common chronic somatic diseases,defined by patients'self-report,were selected to analyze the prevalence of comorbidity,and Logistic regression model was used to analyze the factors influencing the number of somatic comorbidities.Results The total prevalence of somatic comorbidity was 37.0%in 5 422 patients with SCZ,with the highest prevalence of hypertension(22.6%)and diabetes mellitus(13.1%)among 12 somatic diseases selected.Older age was the main factor associated with chronic somatic comorbidities in community schizophrenic patients.The risk of 1-2 comorbidities in patients aged≥60 years was 3.34(95%CI:2.74-4.07)times higher than those aged<45 years,while the risk of≥3 comorbidities was 3.27(95%CI:2.11-5.09)times higher,correspondingly.Female gender,marriage,smoking,and longer duration of illness were also risk factors for comorbidity.Women after menopause had higher risk of comorbidity than perimenopausal women.Conclusion Cardiovascular and metabolic diseases were common somatic comorbidities among schizophrenic patients in Shanghai communities.Older age,female gender,marriage,smoking,and longer duration of illness were risk factors for increasing number of comorbidities.
