Research status of traditional Chinese medicine prevention and treatment of chronic obstructive pulmonary disease based on SIRT1
10.13699/j.cnki.1001-6821.2024.23.023
- VernacularTitle:基于SIRT1探索中医药防治慢性阻塞性肺疾病的研究现状
- Author:
Ping TIAN
1
;
Jin-tian LI
;
Juan LI
;
Yi ZHANG
;
Jian-qing LIANG
;
Rong HU
;
Hao-nan WEN
Author Information
1. 甘肃中医药大学,中医临床学院,甘肃兰州 730000
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
chronic obstructive pulmonary disease;
Sirtuin 1;
inflammation;
apoptosis;
oxidative stress
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(23):3477-3481
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of chronic obstructive pulmonary disease(COPD)involves oxidative stress,inflammatory response,apoptosis,autophagy and aging.Sirtuin 1(SIRT1)plays a crucial role in the pathogenesis and progression of COPD by influencing oxidative stress,apoptosis,inflammation and autophagy.This study aims to investigate the role and mechanism of SIRT1 in COPD progression as well as the potential for prevention and treatment using traditional Chinese medicine,thereby expanding the treatment options for COPD.
