Progress in research on the application of gamma-aminobutyric acid in the treatment of ophthalmic diseases
10.13389/j.cnki.rao.2025.0113
- VernacularTitle:γ-氨基丁酸在眼科疾病治疗中的应用研究进展
- Author:
Ruofan XI
1
;
Zhanglong LI
;
Xinyue CHEN
;
Yuecong SUN
;
Hongsheng BI
;
Ping ZHAO
Author Information
1. 250014 山东省济南市,山东中医药大学
- Publication Type:Journal Article
- Keywords:
γ-aminobutyric acid;
neurotransmitter;
myopia;
amblyopia;
glaucoma;
dry eye syndrome
- From:
Recent Advances in Ophthalmology
2025;45(8):659-662,672
- CountryChina
- Language:Chinese
-
Abstract:
γ-Aminobutyric acid(GABA),a pivotal inhibitory neurotransmitter in the central nervous system,plays an essential role in maintaining normal ocular physiological functions.GABA and its receptors are widely distributed through-out the retina,optic nerve,and visual pathways.Research indicates that GABA dysregulation is implicated in the pathogen-esis and progression of certain ophthalmic disorders.This article provides a comprehensive exploration of the relationship between GABA and ophthalmic diseases,including myopia,amblyopia,glaucoma,and dry eye syndrome.Moreover,the potential mechanisms and recent research advances are discussed.The findings may offer novel options and chances for the diagnosis and treatment of ophthalmic diseases.
