Study of the prognostic value of postoperative patients with severe traumatic brain injury
10.3969/j.issn.1002-0152.2025.06.005
- VernacularTitle:重度创伤性颅脑损伤术后患者预后影响因素研究
- Author:
Hongtao CHEN
1
;
Liping ZHAN
1
;
Bo CHEN
1
Author Information
1. 镇江市第一人民医院神经外科(镇江 212003)
- Publication Type:Journal Article
- Keywords:
Traumatic brain injury;
GCS score;
Rotterdam CT score;
DIC score;
Coagulation function;
Progno-sis;
Influence factor
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(6):349-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze prognostic factors in postoperative patients with severe traumatic brain injury.Methods A retrospective analysis was conducted on the clinical data of patients with severe traumatic brain injury treated at our hospital from January 2020 to May 2024.Based on the Glasgow Outcome Scale scores(GOS)of patients at 3 months postoperatively,they were divided into a favorable prognosis group and an unfavorable prognosis group.The baseline characteristics of the two groups were compared,and the influencing factors associated with early postoperative poor prognosis were analyzed.Results A total of 140 patients were included in the study,including 58 cases in the good prognosis group and 82 cases in the poor prognosis group.There were significant differences in Glasgow coma scale(GCS)score(t=14.137,P=0.002),Rotterdam CT score(t=18.516,P=0.007),and disseminated intravascular coagulation(DIC)score(t=10.428,P=0.008)between the two groups at admission(P<0.05).Multivariate analysis showed that low GCS score(OR=0.273,95%CI:0.126-0.671,P=0.008),high Rotterdam CT Score(OR=1.804,95%CI:1.026-4.557,P=0.018)and high DIC score(OR=1.648,95%CI:1.173-2.424,P=0.020)were important risk factors for poor prognosis.Conclusions Unfavorable postoperative prognosis in severe traumatic brain injury patients correlates with the admission GCS score,Rotterdam CT score,and International Society on Thrombosis and DIC score.A lower GCS score,higher Rotterdam CT score,and higher DIC score at admission were significantly associated with an increased risk of poor postoperative prognosis.