The relationship between cerebral perfusion status,blood pressure variability and prognosis after combined cerebral revascularization surgery in patients with moyamoya disease
10.3969/j.issn.1002-0152.2025.06.004
- VernacularTitle:烟雾病患者接受联合脑血运重建术后脑灌注状态与血压变异性及预后的关系
- Author:
Shao ZHANG
1
;
Liming ZHAO
;
Chaoyue LI
;
Jiangong MA
;
Sen HE
;
Dan LI
;
Xiaobin WANG
Author Information
1. 河南大学第一附属医院神经外科(开封 475000)
- Publication Type:Journal Article
- Keywords:
Moyamoya disease;
Combined with cerebral revascularization;
Cerebral perfusion;
Blood pressure variability;
Prognosis
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(6):342-348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between cerebral perfusion status,blood pressure variability,and prognosis in patients with moyamoya disease following cerebral revascularization.Methods A retrospective analysis was conducted on 108 patients who underwent their first combined cerebral revascularization between January 2019 and July 2022 at the Department of Neurosurgery,First Affiliated Hospital of Henan University,and Henan Provincial People's Hospital.Based on postoperative cerebral perfusion improvement,patients were categorized into a"good"group and a"general"group.Baseline characteristics,key imaging parameters,blood pressure variability,and symptom scores were compared and analyzed between the two groups.Results In this study,there were 55 cases in the good group and 53 cases in the general group.According to the comparative analysis of the postoperative indicators between the good group and the general group,Statistically significant differences were observed in symptom improvement[42(79.25%)vs.52(94.55%)],TIA[22(41.51%)vs.11(20.00%)],and cerebral infarction[6(11.32%)vs.0(0.00%)],mRS score and the Matsushima classification(P<0.05).However,there was no statistically significant difference in the BPV-related index between the two groups of patients before the operation(all P>0.05).When comparing nine blood pressure variability(BPV)-related indices including the mean of 24-hour,daytime,and nighttime systolic blood pressure,coefficient of variability(CV),and average real variability(ARV)between the two groups,no significant differences were observed in the BPV-related indices before surgery between the two groups(P>0.05).The differences in the BPV-related indices before and after surgery(postoperative index-preoperative index)between the two groups were statistically significant(P<0.05).Postoperative cerebral perfusion status was positively correlated with prognosis and negatively correlated with BPV.Conclusion Patients with good improvement in cerebral perfusion status after combined revascularization for moyamoya disease have less blood pressure variability and better prognosis.
