Meta-analysis of the efficacy of hyperbaric oxygen combined with conventional drugs in treating angina pectoris of coronary heart disease
10.3760/cma.j.cn311847-20201215-00463
- VernacularTitle:高压氧联合常规药物治疗冠心病心绞痛疗效的Meta分析
- Author:
Mingming ZHAO
1
;
Yingzhi WANG
1
;
Yan WANG
1
;
Jinzhu ZHANG
1
;
Jixing ZHOU
1
Author Information
1. 276400 山东省临沂，临沂市中心医院心内科
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Coronary heart disease;
Angina pectoris;
Efficacy;
Meta-analysis
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(5):617-621
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the efficacy of hyperbaric oxygen (HBO) combined with comentional drugs in the treatment of angina pectoris caused by coronary heart disease with meta-analysis.Methods:The data on clinical randomized controlled trials (RCTs) of HBO combined with conventional drugs in the treatment of angina pectoris due to coronary heart disease in Cochrane Library, Medline, Embase, Wanfang Data, Cqvip, China National Knowledge Infrastructure (CNKI) were collected, and the time period was from the respective founding day of the above databases to October 2020. Three researchers independently screened the collected RCTs, extracted relevant data, and evaluated the quality of the trials. RevMan 5.4 software was used for meta-analysis.Results:A total of 11 RCTs were included in this study. Meta-analysis results showed that the HBO group was better than the control group in terms of total clinical effectiveness, alleviation of angina symptoms, and improvement in ECG performance.Conclusion:HBO combined with conventional drugs can better alleviate the symptoms of angina pectoris due to coronary heart disease and improve their ECG performance. In the future, high-quality RCTs need to be carried out to verify the conclusion of this study.
