Clinical Characteristics of Pediatric Valvular Heart Disease:A Single Center Analysis
10.3870/j.issn.1672-0741.24.04.024
- VernacularTitle:单中心儿童心脏瓣膜疾病临床特点分析
- Author:
Qianhui MA
1
;
Cong ZHAO
;
Yalan LIU
Author Information
1. 华中科技大学同济医学院附属协和医院儿科,武汉 430022
- Publication Type:Journal Article
- Keywords:
valvular heart disease;
children;
clinical characteristics
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2025;54(1):106-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the complications,etiology,and clinical manifestations between pediatric patients with heart valve disease undergoing surgical treatment.Methods A retrospective analysis was conducted on the clinical data of 169 pediatric patients aged 0-14 years diagnosed with heart valve abnormalities at Wuhan Union Hospital from January 2019 to October 2022.Patients were divided into two groups based on whether they received surgical intervention for valve abnormali-ties:the surgical treatment group and the medical treatment group.Results There were significant differences in age,type and grade of heart failure,club-finger,pneumonia and cough,cardiac morphology,arrhythmia,ventricular septal width and left ven-tricular ejection fraction(all P<0.05).Univariate and multivariate binary logistic regression analyses revealed that left ventricu-lar ejection fraction(OR=1.206,95%CI:1.072-1.357,P<0.05)was an independent risk factor for the surgical treatment group.Conclusion The clinical manifestations of heart valve abnormalities in children are often atypical.Clinicians should ac-tively evaluate the etiology based on clinical symptoms and echocardiographic findings,and develop individualized treatment strategies,either surgical or medical,to prevent the progression of severe heart disease.